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كتب كثيرة لها علاقة بالهندسة الطبية و الصيدلية

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    تاريخ التسجيل: Nov 2008
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    كتب كثيرة لها علاقة بالهندسة الطبية و الصيدلية

    Profiles of Drug Substances, Excipients and Related Methodology
    <DIV class="post-body entry-*******">Book Description:

    Whilst following in the footsteps of previous volumes by presenting comprehensive reviews of drug substances and additional materials, this title also heralds a significant expansion of the scope of the series. Traditional contributions will now also be augmented by publication of critical review chapters that summarize information related to the characterization of drug substances and excipients. This change is required to better meet the needs of the pharmaceutical communtiy and to allow the development of a timely vehicle for publishing review materials on this topic.

    The scope of the Profiles series will encompass review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients.

    * Presents comprehensive reviews covering all aspects of drug development and formulation of drugs
    * Now encompassing critical review chapters
    * Meets the information needs of the drug development community.
    DOWNLOAD LINK:

    Volume:33

    http://rapidshare.com/files/87190761/Pro_Drug_Sub_E_Vol33.zip

    Volume:31

    http://rapidshare.com/files/101822099/Profiles_of_Drug_Substances__Excipients_and_Relate d_Methodology__Volume_31__Profiles_of_D.rar

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    Toxicology of Solvents.
    • Publisher: Rapra Technology Ltd
    • Number Of Pages: 400
    • Publication Date: 2001-12
    • ISBN-10 / ASIN: 1859572960
    • ISBN-13 / EAN: 9781859572962
    • Binding: Hardcover

    About the Author:

    The Medical Toxicology Unit at Guy’s and St Thomas’ Hospital in London is one of the largest specialist toxicology units in the world, providing information about poisoning to health professionals via a 24 hour telephone service. The National Poisons Information Service (London) has been operating for over 30 years and is one of the busiest in the world, handling the majority of the 200,000 calls made each year in the UK.
    All contributors are Poisons Information Specialists at the Medical Toxicology Unit, with extensive experience in advising the UK National Health Service on the consequences of chemical accidents and chemical exposures.
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    http://rapidshare.com/files/148651759/1859572960.rar

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    Pharmaceutical Process Engineering
    Product Description:

    Summarizing fundamental engineering principles and operations critical to converting bulk pharmaceutical products into patient-ready and appropriate drug delivery dosage forms, Pharmaceutical Process Engineering facilitates comprehensive understanding of the practical aspects of drug production in an accessible, step-by-step format. It provides a pharmaceutical perspective on unit operations that improves communication among diverse professionals in the field-from pharmaceutical researchers to chemical and industrial engineers-and fully covers the relationship of pharmaceutical development to the application of key concepts and major unit operations in pharmaceutical engineering.
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    http://rapidshare.com/files/18809247/PPE.rar.html

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    Hansen Solubility Parameters: A User's Handbook, Second Edition
    Product Description:

    Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including polymers, inorganic salts, and biological materials.
    To update his groundbreaking handbook with the latest advances and perspectives, Charles M. Hansen has invited five renowned experts to share their work, theories, and practical applications involving HSPs. New discussions include a new statistical thermodynamics approach for confirming existing HSPs and how they fit into other thermodynamic theories for polymer solutions. Entirely new chapters examine the prediction of environmental stress cracking as well as absorption and diffusion in polymers. Highlighting recent findings on interactions with DNA, the treatment of biological materials also includesskin tissue, proteins, natural fibers, and cholesterol. The book also covers the latest applications of HSPs, such as ozone-safe “designer” solvents, protective clothing, drug delivery systems, and petroleum applications.
    Presenting a comprehensive survey of the theoretical and practical aspects of HSPs, Hansen Solubility Parameters, Second Edition concludes with a detailed discussion on the necessary research, future directions, and potential applications for which HSPs can provide a useful means of prediction in areas such as biological materials, controlled release applications, nanotechnology, and self-assembly.
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    http://rapidshare.com/files/86165210/HSPAUH2ndEdCrc.rar

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    تاريخ التسجيل: Nov 2008
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    Practical Process Research & Development
    Product Description:

    This book will provide a comprehensive, step-by-step approach to organic process research and development in the pharmaceutical, fine
    chemical, and agricultural chemical industries. Process R&D describes the steps taken, following synthesis and evaluation, to bring key
    compounds to market in a cost-effective manner. More people are being hired for work in this area as increasing numbers of drug candidates are
    identified through combinatorial chemistry and high-throughput screening. The book is directed to industrial (primarily organic) chemists, and
    academicians (particularly those involved in a growing number of start-up companies) and students who need insight into industrial process R&D. Current books do not describe hands-on, step-by-step, approaches to solving process development problems, including route, reagent,
    and solvent selection; optimising catalytic reactions; chiral syntheses; and "green chemistry." "Practical Process Research and Development" will be a valuable resource for researchers, managers, and graduate students.

    * Provides insights into generating rugged, practical, cost-effective processes for the chemical preparation of "small molecules"
    * Breaks down process optimization into route, reagent and solvent selection, development of reaction conditions, workup, crystallizations and more
    * Includes over 100 tips for rapid process development
    * Presents guidelines for implementing and troubleshooting processes.
    DOWNLOAD LINK:
    http://rapidshare.com/files/59056383/Practical-Process-Research_Development.rar

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    تاريخ التسجيل: Nov 2008
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    Chiral Separation Techniques (Third Edition)
    Thoroughly revised, with either entirely new or completely updated *******s, this is a practical manual for the small and large-scale preparation of enantiomerically pure products. The result is a vital resource for meeting the highest purity standards in the manufacture of chiral pharmaceuticals, food additives and related compounds. All the approaches covered here are highly relevant to modern manufacturing and quality control schemes in the pharmaceutical and biotech industries, addressing the increasingly important issue of drug safety in view of tougher regulatory standards worldwide.
    DOWNLOAD LINK:
    http://rapidshare.com/files/64288637/CST3.rar

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    Pharmaceutical Production Facilities: Design and Applications
    Pharmaceutical Production Facilities: Design and Applications (Taylor & Francis Series in Pharmaceutical Sciences)
    By Graham Cole

    • Publisher: Informa HealthCare
    • Number Of Pages: 342
    • Publication Date: 1998-02-11
    • ISBN-10 / ASIN: 0748404384
    • ISBN-13 / EAN: 9780748404384
    • Binding: Hardcover

    Product Description:

    Pharmaceutical Production Facilities: Design and Applications considers the concepts and constraints that have to be considered in the design of small, medium and large scale production plants. The layout, along with the flow of materials and personnel through facilities are considered with reference to ensuring compliance with current good manufacturing practice. The book explains how clean rooms have developed, and how recent regulations affect their design. The latest concepts for reducing contamination levels from the operator and the product are discussed. It assess current changes in standards and quality control and makes suggestions for the "ideal production environment" to enable standards to be validated to current standards.
    DOWNLOAD LINK:

    http://rapidshare.com/files/147707299/0748404384.zip

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    تاريخ التسجيل: Nov 2008
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    Bioassay Techniques for Drug Development
    Bioassay Techniques for Drug Development
    By Atta-ur Rahman, MI Choudhary, W Thompson

    • Publisher: Informa HealthCare
    • Number Of Pages: 232
    • Publication Date: 2001-09-14
    • ISBN-10 / ASIN: 9058230511
    • ISBN-13 / EAN: 9789058230515
    • Binding: Hardcover

    Product Description:

    The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassay techniques useful for natural product and pharmaceutical chemists involved in drug discovery and pharmacognosy. The *******s detail a number of enzyme-based assays, cell-based functional bioassays and receptor radioligand binding assays along with detailed descriptions of each type. The majority of these bioassays are presented in a step-by-step format, so they could even be implemented by technical personnel with little background in microbiology, biochemistry or pharmacology.
    DOWNLOAD LINK:
    http://rapidshare.com/files/148356796/9058230511.zip

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    تاريخ التسجيل: Nov 2008
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    Pharmaceutical Product Strategy: Using Dynamic Modeling for Effective Brand Planning
    • Publisher: Informa HealthCare
    • Number Of Pages: 328
    • Publication Date: 2004-12-28
    • ISBN-10 / ASIN: 0849327296
    • ISBN-13 / EAN: 9780849327292
    • Binding: Hardcover

    Product Description:

    Borrowing time-tested Dynamic Modeling (DM) techniques from engineering, the authors illustrate the concept and resulting power of the DM methodology in pharmaceutical product development and brand management. The book examines issues surrounding utilization of information, consistency of assumptions, and the need for approaches that integrate the institutional knowledge of various functional areas as well as leverage the vast amount of secondary data available in the pharmaceutical industry. The authors detail how the DM approach facilitates the brand planning process in a systematic and accessible way. Issues of patient flow dynamics, physician adoption and prescribing patterns, as well as evaluation frameworks for specific treatment regimens are thoroughly examined. A later chapter details the extension of the DM framework to issues of pipeline portfolio management using agent-based modeling techniques and uncertainty formulations.
    DOWNLOAD LINK:

    http://rapidshare.com/files/149010719/0849327296.rar

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